Biochem 523: General Biochemistry |
Fall 2008
Ag Eng B119
|
MWF
11:15-12:05 |
|
 |
| Class |
Day |
Date |
Topics |
Reading
PC
= Pratt & Cornely
PR = Petsko & Ringe
|
Links |
Covered |
Notes |
| Lec 1 |
W |
3 Sep |
Intro to course |
PC 3-21 |
Course info; PRS setup; Quiz 0 |
Q1, E1 |
|
Lec 2 |
F |
5 Sep |
Overview, organic chem review |
PC 24-45; PR 1:0 |
Lec2 pdf & flash |
Q1, E1 |
|
Lec 3 |
M |
8 Sep |
DNA structure |
PC 52-62, 75-79; PR 1:2 |
Lec3 pdf & flash |
Q1, E1 |
|
Lec 4 |
W |
10 Sep |
DNA, PCR, amino acids |
PC 90-103; PR 1:1,3 |
Lec4 pdf & flash |
Q1, E1 |
|
Lec 5 |
F |
12 Sep |
Peptides, 2° structure |
PC 103-112; PR 1:5,6,7,10 |
Lec5 pdf & flash |
Q1, E1 |
|
Lec 6 |
M |
15 Sep |
Quiz 1, 2° structure |
PR 1:4,14,15,16 |
Q1 study guide; Practice Q1;
Q1a key; Q1b key;
Lec6 pdf & flash |
E1 |
Add/Drop deadline |
Lec 7 |
W |
17 Sep |
Conformations, ligand binding |
|
Lec7 pdf & flash |
E1 |
|
Lec 8 |
F |
19 Sep |
Myoglobin & hemoglobin |
PC 116-127 |
Lec8 pdf & flash |
E1 |
|
Lec 9 |
M |
22 Sep |
Actin & myosin |
PC 136-146 |
Lec9 pdf & flash |
Q2, E2 |
|
|
W |
24 Sep |
Exam 1: 7-9pm Goessmann 64 |
Make-ups held during class period* |
E1 study guide; Practice E1;
Practice E1 key |
|
|
Lec 10 |
F |
26 Sep |
Protein purification |
|
Lec10 pdf & flash |
Q2, E2 |
ILE-3 starts |
Lec 11 |
M |
29 Sep |
Protein folding |
PC 112-116; PR U1:3,4,5 |
Lec11 pdf & flash |
Q2, E2 |
|
Lec 12 |
W |
1 Oct |
Structural biology |
PR 5:1,2,3 |
Lec12 pdf & flash |
Q2, E2 |
|
Lec 13 |
F |
3 Oct |
Garman lab research |
PR 1:18, U1:5 |
Lec13 pdf & flash |
Q2, E2 |
|
Lec 14 |
M |
6 Oct |
Reading scientific papers |
Lee 2003 |
Lec14 pdf & flash;
Guide to Lee paper |
Q2, E2 |
ILE-3 due |
Lec 15 |
W |
8 Oct |
Quiz 2, Bioinformatics |
PR 4:6,7,8 |
Q2 study guide; Practice Q2;
Practice Q2 key |
E2 |
ILE-4 starts |
| Lec 16 |
F |
10 Oct |
Enzyme intro |
PC 166-177 |
|
E2 |
|
|
M |
13 Oct |
Holiday |
|
|
|
Columbus Day |
Lec 17 |
T |
14 Oct |
Enzyme mechanism: chymotrypsin |
PC 177-192 |
|
E2 |
Mon Classes |
Lec 18 |
W |
15 Oct |
Enzyme kinetics |
PC 198-213; PR U2:1,2,3 |
|
E2 |
ILE-4 due |
Lec 19 |
F |
17 Oct |
Enzyme kinetics |
PC 213-225; PR U2:4 |
|
E2 |
|
Lec 20 |
M |
20 Oct |
Review |
|
|
|
Prof Garman finishes |
|
W |
22 Oct |
Exam 2: 7-9pm Goessmann 64 |
Make-ups held during class period* |
|
|
Prof Theis starts |
Lec 21 |
F |
24 Oct |
Glucose metabolism |
PC Chapter 10 |
|
Q3, E3 |
|
Lec 22 |
M |
27 Oct |
|
Q3, E3 |
|
Lec 23 |
W |
29 Oct |
|
Q3, E3 |
|
Lec 24 |
F |
31 Nov |
Connection 1: Theis lab |
Original literature |
|
Q3, E3 |
|
Lec 25 |
M |
3 Nov |
Citric acid cycle |
PC Chapter 11 |
|
E3 |
|
Lec 26 |
W |
5 Nov |
|
E3 |
Quiz 3 |
Lec 27 |
F |
7 Nov |
|
E3 |
|
Lec 28 |
M |
10 Nov |
Connection 2 |
PC Chapter 15 (parts) |
|
E3 |
|
|
W |
12 Nov |
No Class |
|
|
|
Tues Classes |
Lec 29 |
F |
14 Nov |
ATP synthesis
(Oxidative phosphorlyation
and photosynthesis) |
PC Chapter 12 |
|
Q4, E4 |
|
Lec 30 |
M |
17 Nov |
|
Q4, E4 |
|
|
W |
19 Nov |
Make-ups held during class period* |
|
Q4, E4 |
Exam 3: 7-9 Gsmn 64 |
Lec 31 |
F |
21 Nov |
PC Chapter 13 (parts)
|
|
Q4, E4 |
|
Lec 32 |
M |
24 Nov |
|
Q4, E4 |
|
Lec 33 |
W |
26 Nov |
Connection 3 |
Original literature |
|
Q4, E4 |
|
|
F |
28 Nov |
Holiday |
|
|
|
Thanksgiving |
Lec 34 |
M |
1 Dec |
Lipid metabolism |
PC Chapter 14 |
|
E4 |
|
Lec 35 |
W |
3 Dec |
|
E4 |
Quiz 4 |
Lec 36 |
F |
5 Dec |
|
E4 |
|
Lec 37 |
M |
8 Dec |
Using ATP: Example 1 |
Original literature |
|
E4 |
|
Lec 38 |
W |
10 Dec |
Using ATP: Example 2 |
Original literature |
|
E4 |
|
Lec 39 |
F |
12 Dec |
Review |
|
|
|
|
|
T |
16 Dec |
Exam 4: 1:30-3:30pm ECSC 119 |
|
|
|
During Finals week |
*Make-up exams must be arranged in advance.
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